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Evaluating Plasmonic Transport in Current-carrying Silver Nanowires
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Nocturia: Evaluation and Current Management Strategies.

Casey G Kowalik1, Joshua A Cohn2, Sophia Delpe1

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|June 27, 2018
PubMed
Summary
This summary is machine-generated.

Nocturia, often caused by nocturnal polyuria, significantly impacts life quality. Desmopressin acetate nasal spray effectively reduces nighttime voids in adults experiencing frequent awakenings.

Keywords:
Benign prostatic hyperplasiaDesmopressinNocturiaNocturnal polyuriaOveractive bladder

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Area of Science:

  • Urology
  • Sleep Medicine
  • Pharmacology

Background:

  • Nocturia significantly affects patient quality of life.
  • It can indicate underlying systemic diseases.
  • Common causes include sleep disorders, bladder storage issues, and polyuria.

Purpose of the Study:

  • To review the assessment and treatment of nocturia.
  • To highlight the role of desmopressin acetate nasal spray for nocturnal polyuria.

Main Methods:

  • Initial assessment involves detailed history, physical examination, and frequency-volume charts.
  • Pharmacological treatments include alpha-blockers and antimuscarinics for specific causes.
  • Desmopressin acetate nasal spray is approved for nocturia due to nocturnal polyuria.

Main Results:

  • Desmopressin acetate nasal spray (Noctiva™) was FDA-approved in 2017.
  • Clinical trials demonstrated efficacy in reducing nocturnal voids by ≥50% in up to 49% of patients.
  • This treatment is indicated for adults awakening at least twice nightly.

Conclusions:

  • Nocturia management requires identifying underlying causes.
  • Desmopressin acetate nasal spray offers a targeted treatment for nocturia stemming from nocturnal polyuria.
  • This medication improves quality of life for affected adults.