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Updated: Feb 8, 2026

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
Published on: May 11, 2014
Evaluation of Dysplasia in Barrett Esophagus
Seth A Gross1, Joseph Kingsbery1, Janice Jang1
1Dr Gross is an associate professor of medicine, Dr Kingsbery and Dr Jang are resident physicians, and Dr Lee and Dr Khan are assistant professors of medicine in the Division of Gastroenterology and Hepatology at NYU Langone Health in New York, New York.
Abstract:
Barrett esophagus (BE) is the precursor lesion to adenocarcinoma of the esophagus. The current surveillance strategy of 4-quadrant Seattle protocol biopsies has been associated with sampling error and missing higher-risk lesions, and there is often less adherence to endoscopic surveillance with long segments. Advancements in endoscopic imaging and sampling techniques allow for better surveillance of BE, particularly when assessing for dysplasia. This article highlights the key endoscopic imaging and sampling advancements in the evaluation of dysplasia in BE.
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