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Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

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The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
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The primary microtubule organizing center (MTOC) in animal cells is the centrosome. A centrosome has two cylindrical centrioles at its core. Each centriole consists of nine sets of three microtubules held together by proteins. The centrioles are positioned at right angles to each other and surrounded by a shapeless protein cloud called the pericentriolar matrix, or pericentriolar material (PCM).
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The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
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Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
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The process of chromosome duplication during cell division requires genome-wide disruption and re-assembly of chromatin. The chromatin structure must be accurately inherited, reassembled, and maintained in the daughter cells to ensure lineage propagation.
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Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
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Acute single appendicitis in a female with a duplicated appendix.

Kusay Ayoub1, Sadallah Kayali1, M Fateh Dabbagh2

  • 1Department of Surgery, Aleppo University Hospital, Aleppo, Syria.

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|June 27, 2018
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Summary

Appendiceal duplication is a rare congenital anomaly. This case highlights acute inflammation in one of two appendices, emphasizing the need for surgical awareness of this condition.

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Area of Science:

  • Gastroenterology
  • Surgical Pathology

Background:

  • Appendiceal duplication is a rare congenital anomaly, affecting 0.004-0.009% of the population.
  • Preoperative diagnosis is challenging, with diagnosis often confirmed intraoperatively or postoperatively via histopathology.

Observation:

  • A case report of a female patient presenting with acute inflammation in one of two duplicated appendices.
  • The anomaly was identified during surgical intervention.

Findings:

  • Histopathological examination confirmed the presence of a duplicated appendix.
  • Inflammation was localized to one of the two appendiceal structures.

Implications:

  • Surgeons must consider appendiceal duplication in differential diagnoses to prevent misdiagnosis and ensure appropriate management.
  • Awareness of this rare anomaly is crucial to avoid potential ethical and legal complications in patient care.