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Pericarditis due to Neisseria meningitidis serogroup W135

Takashi Shinha1, Hiroshi Fujita2

  • 1Internal Medicine and Infectious Diseases, Inc, 1010 S. King St. Suite 111, Honolulu, HI 96814, United States.

Idcases
|June 27, 2018
PubMed

Insights

Neisseria meningitidis can cause pericarditis, a rare but serious heart inflammation. Serogroup W135 is particularly linked to this condition, often as a complication of disseminated meningococcal disease.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Microbiology

Background:

  • Neisseria meningitidis is a primary cause of bacterial meningitis.
  • Extra-meningeal involvement, such as pericarditis, is less common but recognized.
  • Serogroups C and W135 are more frequently associated with extra-meningeal disease, including pericarditis.

Purpose of the Study:

  • To report a case of pericarditis caused by Neisseria meningitidis serogroup W135.
  • To highlight the association between Neisseria meningitidis serogroup W135 and secondary pericarditis.
  • To underscore the potential severity of meningococcal pericarditis, including cardiac tamponade and cardiogenic shock.

Main Methods:

  • Case report presentation.
  • Literature review on Neisseria meningitidis pericarditis etiologies and serogroup associations.

Main Results:

  • A case of pericarditis secondary to disseminated meningococcal disease caused by Neisseria meningitidis serogroup W135 is presented.
  • Meningococcal pericarditis can arise from primary infection, disseminated meningococcemia, or as a reactive immunologic complication.
  • Massive pericardial effusion and cardiac tamponade are significant potential complications.

Conclusions:

  • Neisseria meningitidis serogroup W135 can cause secondary pericarditis.
  • Prompt recognition and management of meningococcal pericarditis are crucial due to potential life-threatening complications.
  • Further research into the specific mechanisms and management strategies for Neisseria meningitidis-related pericarditis is warranted.
Keywords:
Neisseria meningitidisPericarditisSerogroup W135

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