Related Experiment Video
Updated: Feb 8, 2026

Intraperitoneal Injection into Adult Zebrafish
Published on: August 30, 2010
The effects of intraperitoneal chemotherapeutic agents on adhesion formation
Purpose:
Intra-abdominal adhesions are a major complication of healing. Furthermore these adhesions may cause morbidity and sometimes mortality for patients, and also are a financial burden to the health system.
Materials And Methods:
Cecum abrasion was performed in all rats and solutions containing saline to group 1, 5-fluorouracil to group 2, cisplatin to group 3, paclitaxel to the group 4, and mitomycin-C were administered into the abdomen of the groups, respectively. The intra-abdominal adhesions were scored after the macroscopic evaluation.
Results:
Among the chemotherapeutic drugs, paclitaxel significantly increases occurring of intra-abdominal adhesions in comparison with the control group and the other drugs according to the evaluation of scoring and statistical studies.
Conclusion:
It is suggested to use the drugs which have a proven anti-adhesion feature or barriers to the patients who are going to be applied intraperitoneal chemotherapy with paclitaxel.
Related Concept Videos
Adhesion
Capillary action is a result of water’s adhesive tendencies. When a narrow...
Buffer Effectiveness
The buffer capacity is the amount of acid or base that can be added to a given volume...
Subviral Agents
Cell Adhesion in Plants
Pectins are complex heteropolymers mainly composed of negatively-charged α-D-glucopyranosyl uronic acid and some neutral glycosyl residues such as α-L-rhamnopyranose, α-L-arabinofuranose,...
Formation of Species
Solution Formation
This selective...

