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Intracardiac Flow at 4D CT: Comparison with 4D Flow MRI

Jonas Lantz1, Vikas Gupta1, Lilian Henriksson1

  • 1From the Division of Cardiovascular Medicine, Department of Medical and Health Sciences (J.L., V.G., T.E.), Center for Medical Image Science and Visualization (CMIV) (J.L., V.G., L.H., M.K., A.P., C.J.C., T.E.), Division of Radiology, Department of Medical and Health Sciences (L.H., A.P.), Division of Applied Thermodynamics and Fluid Mechanics, Department of Management and Engineering (M.K.), and Department of Clinical Physiology, Department of Medical and Health Sciences (C.J.C.), Linköping University, SE-58183 Linköping, Sweden. From the 2017 RSNA Annual Meeting.

Radiology
|June 27, 2018
PubMed

Insights

Four-dimensional flow CT accurately assesses intracardiac blood flow patterns, showing results comparable to four-dimensional flow MRI. This CT technique offers a reliable alternative for evaluating complex blood flow dynamics within the heart.

Area of Science:

  • Cardiovascular Imaging
  • Medical Physics
  • Biomedical Engineering

Background:

  • Four-dimensional (4D) flow MRI is the reference standard for assessing intracardiac blood flow.
  • Developing advanced CT techniques for similar assessments is crucial for broader clinical application.

Purpose of the Study:

  • To compare the accuracy of four-dimensional (4D) flow CT with 4D flow MRI in evaluating intracardiac blood flow patterns.
  • To determine the quantitative and qualitative similarities between the two imaging modalities.

Main Methods:

  • Prospective study of 12 participants comparing 4D flow CT and 4D flow MRI data.
  • Quantification of flow patterns, rates, stroke volume, kinetic energy, and flow components for both techniques.
  • Comparison using linear regression and statistical analysis for correlation and variability.

Main Results:

  • 4D flow CT demonstrated qualitatively similar cardiac flow patterns to 4D flow MRI, confirmed by observer grading.
  • High correlations were found for peak flow rate (r=0.98), stroke volume (r=0.81), and kinetic energy at peak systole (r=0.95).
  • Significant correlations were also observed for direct (r=0.93) and residual (r=0.87) flow components.

Conclusions:

  • Four-dimensional flow CT provides a reliable assessment of intracardiac blood flow patterns.
  • The quantitative and qualitative results from 4D flow CT are comparable to the established 4D flow MRI standard.
  • 4D flow CT presents a promising alternative for detailed intracardiac hemodynamics evaluation.

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