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Related Concept Videos

Globular and Fibrous Proteins02:21

Globular and Fibrous Proteins

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Many proteins can be classified into two distinct subtypes - globular or fibrous. These two types differ in their shapes and solubilities.
Globular proteins are also known as spheroproteins and typically are approximately round in shape. They contain a mix of amino acid types and contain differing sequences in their primary structures. Globular proteins have many different functions, such as enzymes, cellular messengers, and molecular transporters. These roles often require the proteins to be...
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Fibrous proteins are either long and narrow proteins or assemble to form long and thin structures. They contain repetitive units and usually consist of either alpha helices or beta sheets and, in rare cases, a mix of both. The amino acids in the primary structure often consist of repeating amino acid sequences. The role of fibrous proteins is primarily structural. Many are located in the extracellular matrix and are present in connective tissues to impart strength and joint mobility. They are...
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Structural Joints: Fibrous Joints01:03

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Fibrous joints are a type of joint where the bones are connected by fibrous connective tissue. These joints provide stability and minimal to no movement between the articulating bones. There are three types of fibrous joints.
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Signal processing techniques are essential for accurately converting continuous signals to digital formats and vice versa. When a continuous signal is sampled with a period T, the resulting sampled signal exhibits replicas of the original spectrum in the frequency domain, spaced at intervals equal to the sampling frequency. To handle this sampled signal, a zero-order hold method can be applied, which creates a piecewise constant signal by retaining each sample's value until the next...
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Protein Complex Assembly

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Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
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Related Experiment Video

Updated: Feb 8, 2026

Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach
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Fibrous Dysplasia: A Complex Maxillary Reconstruction.

Elidon Mici1, Evaristo Belli

  • 1Unit of Maxillo-Facial Surgery, University of Rome "Sapienza," Sant'Andrea Hospital, Rome, Italy.

The Journal of Craniofacial Surgery
|June 27, 2018
PubMed
Summary
This summary is machine-generated.

Fibrous dysplasia, a benign bone tumor, can affect the jaw. This case details surgical removal of a large maxillary fibrous dysplasia and reconstruction using a custom implant.

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Area of Science:

  • Oral and Maxillofacial Surgery
  • Skeletal Pathology
  • Neurosurgery

Background:

  • Fibrous dysplasia is a benign skeletal tumor with monostotic and poliostotic forms.
  • The maxilla and mandible are frequently affected facial bones.

Observation:

  • A 63-year-old patient presented with a 20-year history of progressive left maxillary neoformation.
  • The neoformation was diagnosed as a huge maxillary fibrous dysplasia.

Findings:

  • Surgical management involved a total maxillectomy.
  • Reconstruction utilized a custom-made midface implant combined with temporal and pericranial flaps.

Implications:

  • This case highlights a rare presentation of extensive maxillary fibrous dysplasia.
  • Successful reconstruction demonstrates the efficacy of custom implants and flap techniques for complex midface defects.