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Published on: July 26, 2010
The Introduction of Innovations in Neurovascular Care: Patient Selection and Randomized Allocation
Robert Fahed1, Tim E Darsaut2, Jean Raymond3
1Department of Interventional Neuroradiology, Rothschild Foundation Hospital, Paris, France; Service of Neuroradiology, Department of Radiology, Centre Hospitalier de l'Université de Montréal, Notre-Dame Hospital, Montreal, Quebec, Canada.
Abstract:
Most neurovascular innovations have been introduced by using case series followed by observational studies. A better approach would be a pragmatic randomized trial. Two important aspects of trial design, patient selection and randomized allocation, remain poorly understood. We discuss the role trial methodology can play in the protection of patients being offered innovative treatments.
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