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Updated: Feb 8, 2026
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Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
Published on: August 4, 2018
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Evaluating inner retinal dimples after inner limiting membrane removal using multimodal imaging of optical coherence
Jingjing Liu1, Yiye Chen1, Shiyuan Wang1
1Department of Ophthalmology, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
BMC Ophthalmology
|June 28, 2018
Summary
Inner retinal dimples are common after inner limiting membrane peeling for macular holes. Highly myopic eyes show more severe defects, suggesting a link between myopia and post-surgical complications.
Area of Science:
- Ophthalmology
- Retinal Surgery
- Medical Imaging
Background:
- Inner limiting membrane (ILM) peeling is a surgical technique for macular holes.
- Assessing postoperative complications like inner retinal dimples is crucial.
- Understanding the relationship between preoperative conditions and dimple formation is important.
Purpose of the Study:
- To evaluate inner retinal dimples after ILM peeling for lamellar macular hole (LMH) and full-thickness macular hole (FTMH).
- To utilize multiple spectral-domain optical coherence tomography (OCT) imaging modes for assessment.
- To correlate dimple formation with preoperative vitreoretinal interface conditions.
Main Methods:
- Retrospective study of 38 eyes from 35 patients undergoing surgery for LMH and FTMH.
- Postoperative inner retinal dimples identified using en face OCT and cross-sectional OCT images.
- Comparison of demographic and clinical characteristics between eyes with and without defects.
Main Results:
- Inner retinal defects observed in 68% of eyes post-surgery.
- Defects appeared as dark spots on en face OCT ILM layer images, correlating with dimples on cross-sectional OCT.
- Progression of defects noted in 19% of cases, with a potential eccentric growth pattern.
- Highly myopic eyes showed a significant association with more severe inner retinal defects.
Conclusions:
- En face spectral-domain OCT offers comprehensive visualization of inner retinal dimples.
- High myopia appears to be a risk factor for developing more severe inner retinal defects after ILM peeling.
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