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Updated: Feb 8, 2026
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Generation of Recombinant Human IgG Monoclonal Antibodies from Immortalized Sorted B Cells
Published on: June 5, 2015
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The Increasingly Human and Profitable Monoclonal Antibody Market
António L Grilo1, A Mantalaris2
1Biological Systems Engineering Laboratory, Centre for Process Systems Engineering, Department of Chemical Engineering, Imperial College London, Exhibition Road, London SW7 2AZ, UK; ORCID: https://orcid.org/0000-0002-8592-8304.
Trends in Biotechnology
|June 28, 2018
Summary
The monoclonal antibody (mAb) market has doubled in five years, now featuring more human antibodies and bispecific therapies. Competition from biosimilars is also increasing.
Area of Science:
- Biotechnology
- Pharmaceutical Market Analysis
- Immunotherapy
Background:
- The monoclonal antibody (mAb) market has experienced significant expansion and evolution over the last five years.
- Key shifts include market size doubling, a rise in fully human antibody dominance, and the introduction of bispecific molecules.
Purpose of the Study:
- To provide a comprehensive summary of the current monoclonal antibody market.
- To analyze market trends concerning therapeutic applications, antibody types, company dominance, manufacturing, and emerging markets.
Main Methods:
- Market analysis based on recent industry data.
- Review of therapeutic applications, mAb structures, and key market players.
- Examination of manufacturing sites and geographical market expansion.
Main Results:
- The mAb market has doubled in size within the past five years.
- Fully human monoclonal antibodies and bispecific molecules now dominate the market.
- Increased competition from biosimilars has emerged as a notable trend.
Conclusions:
- The monoclonal antibody landscape is dynamic, characterized by rapid growth and technological advancements.
- Market dominance has shifted towards more sophisticated antibody formats.
- The competitive environment is intensifying due to biosimilar entries and evolving therapeutic strategies.
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