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Author Spotlight: Optimizing Growth Factors for Production of Biotechnologically Relevant Secondary Metabolites
Published on: October 25, 2024
[Evaluation of the effect of concentrated growth factor in oral rehabilitation]
1Department of Stomatology, The Affiliated Hospital of Qingdao University. Qingdao 266000, Shandong Province, China.
Purpose:
To investigate the clinical effect of concentrated growth factor (CGF) in oral cavity repair.
Methods:
From February 2013 to February 2016 in our hospital, 60 patients with insufficient bone underwent dental implantation. CGF was used alone in 27 patients (CGF group), CGF was used with autologous bone or bone material in 33 patients (CGF mixed group). Bone repair was observed and evaluated. SPSS19.0 software package was used for statistical analysis.
Results:
Wound healing time in CGF group and CGF mixed group (8.43±0.72) d and (8.04±0.98) d, wound healing rate was 92.60% in CGF group and 90.91% in CGF group, the difference was not statistically significant (P>0.05); Implant success rate in CGF group and CGF mixed group was 92.31% and 96.36% , respectively. The difference was not statistically significant (P>0.05).
Conclusions:
CGF has good effect in repair of bone defect, and the long-term effect is stable. It is a simple and safe material for bone regeneration.
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