Related Experiment Video

Updated: Feb 8, 2026

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

25.0K

Long-term Management of the Arterial Switch Patient

Jared Kirzner1, Altaf Pirmohamed1, Jonathan Ginns1

  • 1Cornell Center for Adult Congenital Heart Disease, Departments of Medicine and Pediatrics, Division of Cardiology, New York Presbyterian Hospital, Weill Cornell Medicine, 520 East 70th Street, Starr 425, New York, NY, 10021, USA.

Current Cardiology Reports
|June 28, 2018
PubMed

Insights

This review focuses on managing dextro-transposition of the great arteries (D-TGA), a cyanotic congenital heart disease. Early detection and prevention of complications like stenosis and regurgitation are crucial for long-term patient health.

Area of Science:

  • Cardiology
  • Pediatric Cardiology
  • Congenital Heart Disease

Background:

  • Dextro-transposition of the great arteries (D-TGA) accounts for approximately 3% of all congenital heart disease (CHD) and 20% of cyanotic CHD.
  • The arterial switch operation (ASO) has been the standard repair for D-TGA since the late 1980s, offering superior long-term outcomes compared to the Mustard/Senning operation.

Purpose of the Study:

  • To review the management of patients with D-TGA.
  • To focus on identifying and preventing adverse events and long-term complications.

Main Methods:

  • Review of current literature and clinical guidelines for D-TGA management.
  • Emphasis on long-term follow-up strategies.
  • Utilization of echocardiography and advanced imaging (CT/MRI).

Main Results:

  • The arterial switch operation (ASO) is associated with superior long-term survival and complication rates.
  • Common long-term complications include pulmonary stenosis, coronary artery stenosis, and neo-aortic regurgitation.
  • Regular follow-up with adult congenital heart disease specialists is recommended.

Conclusions:

  • Long-term surveillance is essential for all D-TGA patients.
  • Prompt evaluation of new symptoms or functional decline is critical for effective management.
  • Preventing and treating sequelae like stenosis and regurgitation improves patient outcomes.
Abstract

Keywords:
Adult congenital heart diseaseArterial switch operationCongenital heart surgeryJatene arterial switchTransposition of the great arteriesVentriculoarterial discordanced-Transposition

More Related Videos

Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics10:42

Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics

Published on: June 17, 2022

3.5K
Targeting the Rat's Small Bowel: Long-Term Infusion into the Superior Mesenteric Artery07:12

Targeting the Rat's Small Bowel: Long-Term Infusion into the Superior Mesenteric Artery

Published on: April 8, 2021

5.2K

Related Concept Videos

Switching of BJT01:22

Switching of BJT

Switching behavior in Bipolar Junction Transistors (BJTs) is a fundamental aspect utilized in various electronic circuits, particularly for digital logic applications like switches and amplifiers. In a typical switching circuit, a BJT alternates between cut-off and saturation modes, corresponding to the "off" and "on" states, respectively, thus behaving like an ideal switch.
Cut-off Mode ("Off" State): In this state, both the emitter-base and collector-base junctions are...
867
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
417
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

 The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
389
Long-term Depression01:05

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
33.3K
Long-term Depression01:03

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
3.4K
Long-term Potentiation01:35

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
58.7K