Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Proteins: From Genes to Degradation02:11

Proteins: From Genes to Degradation

14.5K
Within a biological system, the DNA encodes the RNA, and the nucleotide sequence in the RNA further defines the amino acid sequence in the protein. This is referred to as “The Central Dogma of Molecular Biology” - a term coined by Francis Crick.  Central dogma is a firm principle in biology that defines the flow of genetic information within any life form. The two fundamental steps in central dogma are - transcription and translation.
Transcription is the synthesis of RNA...
14.5K
Proteins: From Genes to Degradation02:11

Proteins: From Genes to Degradation

4.5K
4.5K
Phase I Reactions: Hydrolytic Reactions01:15

Phase I Reactions: Hydrolytic Reactions

686
Hydrolysis, a cornerstone of phase I biotransformation reactions, uses water to cleave chemical bonds. This process is pivotal in drug metabolism, generating more polar metabolites that can be easily excreted.
An important hydrolytic reaction is ester hydrolysis. Ester bonds, often found in prodrugs, are broken down, increasing the solubility of drugs like aspirin and lidocaine for more straightforward elimination. Amide hydrolysis is another critical reaction, targeting amide bonds prevalent...
686
Regulated Protein Degradation02:58

Regulated Protein Degradation

8.9K
It is vital to regulate the activity of enzymatic as well as non-enzymatic proteins inside the cell. This can be achieved either through creating a balance between their rate of synthesis and degradation or regulating the intrinsic activity of the protein. Both these regulation mechanisms play an essential role in the normal functioning of cells.
Protein degradation plays two important roles in the cells. It helps to protect cells from misfolded or damaged proteins before they lead to a...
8.9K
Regulated Protein Degradation02:58

Regulated Protein Degradation

3.2K
3.2K
Electron Affinity03:07

Electron Affinity

43.4K
The electron affinity (EA) is the energy change for adding an electron to a gaseous atom to form an anion (negative ion).
43.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

From materials to systems: recent advances on electrochemical sensors for capsaicin detection.

The Analyst·2026
Same author

A smart nail platform for wireless subsoil health monitoring via unmanned aerial vehicle-assisted radio frequency interrogation.

Nature communications·2025
Same author

Study on fold formation mechanism and process optimization in multi-directional die forged valve bodies.

PloS one·2025
Same author

Control of epithelial homeostasis by apical polarity: it takes a network.

Biochemical Society transactions·2025
Same author

Flexible and Anisotropic Large-Area Piezoresistive Films for High Spatial Resolution Pressure Mapping.

ACS applied materials & interfaces·2025
Same author

IARC Workshop on the Key Characteristics of Carcinogens: Assessment of End Points for Evaluating Mechanistic Evidence of Carcinogenic Hazards.

Environmental health perspectives·2025

Related Experiment Video

Updated: Feb 8, 2026

A Fabrication Method for Highly Stretchable Conductors with Silver Nanowires
07:50

A Fabrication Method for Highly Stretchable Conductors with Silver Nanowires

Published on: January 21, 2016

10.4K

Laser-Enabled Processing of Stretchable Electronics on a Hydrolytically Degradable Hydrogel.

Rahim Rahimi1,2, Siamak Shams Es-Haghi1,3, Shirisha Chittiboyina4

  • 1Birck Nanotechnology Center, Purdue University, West Lafayette, IN, 47907-2057, USA.

Advanced Healthcare Materials
|June 28, 2018
PubMed
Summary
This summary is machine-generated.

Researchers developed highly stretchable and degradable electronics using a photo-crosslinkable hydrogel. This innovation is ideal for temporary medical implants that safely dissolve after use.

Keywords:
degradablelaser processingstretchable electronicsstretchable hydrogels

More Related Videos

Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications
10:18

Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications

Published on: May 17, 2022

6.8K
Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
12:07

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

14.1K

Related Experiment Videos

Last Updated: Feb 8, 2026

A Fabrication Method for Highly Stretchable Conductors with Silver Nanowires
07:50

A Fabrication Method for Highly Stretchable Conductors with Silver Nanowires

Published on: January 21, 2016

10.4K
Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications
10:18

Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications

Published on: May 17, 2022

6.8K
Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
12:07

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

14.1K

Area of Science:

  • Materials Science
  • Biomedical Engineering
  • Electronics Engineering

Background:

  • Degradable electronics are emerging for short-term medical implants.
  • Existing degradable electronics often lack elasticity, limiting their use in dynamic biological tissues.

Purpose of the Study:

  • To demonstrate a novel photo-crosslinkable hydrogel integrated with stretchable and degradable electronics.
  • To overcome the limitations of non-elastic degradable electronic systems for biomedical applications.

Main Methods:

  • Fabrication using laser micromachining of conductive patterns on hydrogel under ambient conditions.
  • Investigation of hydrogel robustness, degradation rates, and laser-processed circuit performance in various solutions.
  • Biocompatibility assessment using non-neoplastic and cancer cell lines in 2D and 3D cultures.

Main Results:

  • A highly stretchable and degradable hydrogel-based electronic system was successfully fabricated.
  • Systematic investigation confirmed the robustness and tunable degradation of the hydrogel and circuits.
  • Biocompatibility tests confirmed the safety of the hydrogel, its byproducts, and zinc metal.

Conclusions:

  • The developed photo-crosslinkable hydrogel system offers a promising platform for advanced degradable electronics.
  • The technology is suitable for temporary biomedical applications, demonstrated by a wireless thermal energy delivery device.
  • This work paves the way for elastic, degradable electronic implants compatible with soft biological tissues.