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Management of Radiation Proctitis
Lameese Tabaja1,2, Shafik M Sidani3,4
1Department of Colon and Rectal Surgery, Digestive Disease Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates. TabajaL@clevelandclinicabudhabi.ae.
Digestive Diseases and Sciences
|June 28, 2018
Summary
Radiation proctitis, a rectal complication of pelvic radiation therapy, lacks clear management guidelines. This review discusses medical, endoscopic, and surgical treatments for this challenging condition.
Area of Science:
- Gastroenterology
- Radiation Oncology
Background:
- Radiation proctitis is rectal mucositis caused by radiation therapy for pelvic cancers.
- Current management strategies are limited due to a lack of established guidelines and research.
Purpose of the Study:
- To review and discuss various treatment modalities for chronic radiation proctitis.
- To provide insights into managing this challenging condition.
Main Methods:
- Literature review of medical, endoscopic, and surgical treatment options.
- Discussion of the efficacy and safety of different interventions.
Main Results:
- Medical options like anti-inflammatories, antioxidants, formalin, and hyperbaric oxygen may alleviate bleeding.
- Endoscopic argon plasma coagulation is effective and safe.
- Surgery is reserved for severe or refractory cases.
Conclusions:
- Effective management of radiation proctitis requires a tailored approach based on treatment modality.
- Further research is needed to establish definitive guidelines for managing radiation-induced rectal injury.
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