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Pulmonary Hemorrhage in Children: Etiology, Clinical Profile and Outcome
Channa de Silva1, Aparna Mukherjee1, Kana Ram Jat1
1Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India.
Insights
Pulmonary hemorrhage in children has diverse causes, including idiopathic pulmonary hemosiderosis and post-infectious complications. Understanding these pediatric pulmonary hemorrhage etiologies guides effective investigation and treatment strategies.
Area of Science:
- Pediatric Pulmonology
- Respiratory Medicine
Background:
- Pulmonary hemorrhage is a serious condition in children.
- Etiology, clinical presentation, and management vary widely.
Purpose of the Study:
- To describe the etiology, clinical profile, treatment, and outcomes of pediatric pulmonary hemorrhage.
- To inform diagnostic and therapeutic approaches for children with this condition.
Main Methods:
- Retrospective chart review of pediatric patients with pulmonary hemorrhage.
- Study conducted at a tertiary care hospital in North India.
Main Results:
- 44 children were included; common etiologies were idiopathic pulmonary hemosiderosis (36.4%), post-infectious complications (25%), immune-mediated disorders (18.2%), cardiac/vascular disorders (15.9%), and airway pathologies (4.5%).
- Treatment varied by etiology, including medications, bronchial artery embolization, and surgery.
- Idiopathic pulmonary hemosiderosis and immune-mediated groups received steroids, with the latter showing slower response and more relapses.
Conclusions:
- Identifying key etiological categories of pediatric pulmonary hemorrhage is crucial.
- This aids in practical planning of investigations and management for diverse causes.
Objective:
To describe etiology, clinical profile, treatment and outcome of children with pulmonary hemorrhage.
Methods:
A chart review of children with pulmonary hemorrhage attending Pediatric Pulmonology services of a tertiary care hospital in North-India was done.
Results:
Data of 44 children (mean age 59.2 ± 32.1 mo; 28 boys) were included for the study. Possible idiopathic pulmonary hemosiderosis 16 (36.4%), post infectious complications 11 (25%), immune mediated disorders 8 (18.2%), cardiac and vascular disorders 7 (15.9%), and airway pathologies 2 (4.5%) were the etiologies of pulmonary hemorrhage. Treatment options like medications, bronchial artery embolization and surgical resections were offered according to the etiology. Children with idiopathic pulmonary hemosiderosis and those with immune mediated diseases were treated with systemic steroids and steroid sparing agents; the latter group took longer time to respond and had more relapses.
Conclusions:
Identification of main etiological categories of pulmonary hemorrhage in children could be useful to plan investigations and management of wide range of causes in more practical way.
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