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[Study on classic preparations].

Mao-Bo Du1, Shu-Zhi Liu1

  • 1Institue of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

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|June 29, 2018
PubMed
Summary
This summary is machine-generated.

This study systematically reviewed classic Chinese medicine preparations from the Treatise on Febrile Diseases, detailing drug doses, solvents, excipients, and processing methods to support modern drug development.

Keywords:
Chinese medicine lawTreatise on Febrile Diseaseclassic preparationsprocess parameters

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Area of Science:

  • Traditional Chinese Medicine
  • Pharmacology
  • Drug Development

Background:

  • Classic preparations from the Treatise on Febrile Diseases are foundational in Traditional Chinese Medicine.
  • Understanding their process parameters is crucial for modern pharmaceutical research and development.

Purpose of the Study:

  • To systematically investigate and document the process parameters of classic preparations from the Treatise on Febrile Diseases.
  • To provide literature evidence and technical support for drug research and development.

Main Methods:

  • Systematic review of classic preparations, focusing on drug dose, solvents, excipients, and processing techniques.
  • Comparison of historical drug doses with modern pharmacopoeial standards.

Main Results:

  • Identified inconsistencies in drug dosage between historical texts and the Pharmacopoeia of the People's Republic of China 2015.
  • Classified solvents into wine and water (eight types of water, four types of wine) and excipients into rice and honey.
  • Detailed various processing methods for powders, pills, and decoctions.

Conclusions:

  • Clarified key process parameters for classic preparations, including drug dose, solvents, excipients, and processing methods.
  • The findings provide essential literature evidence and technical support for the research and development of Traditional Chinese Medicine drugs.