Improved rates of antimicrobial stewardship interventions following implementation of the Epic antimicrobial

Natasha N Pettit1, Zhe Han1, Anish R Choksi1

  • 11Department of Pharmacy,University of Chicago Medical Center,Chicago,Illinois.

Insights

The Epic antimicrobial stewardship module (EAM) increased antimicrobial stewardship program reviews and interventions. This tool effectively reduced antimicrobial use while maintaining positive clinical outcomes.

Area of Science:

  • Infectious Diseases
  • Health Informatics
  • Clinical Pharmacy

Background:

  • Antimicrobial resistance necessitates robust antimicrobial stewardship programs (ASPs).
  • Electronic health record (EHR) modules can support ASP activities.
  • The Epic antimicrobial stewardship module (EAM) is a tool designed to enhance ASP interventions.

Purpose of the Study:

  • To assess the impact of implementing the Epic antimicrobial stewardship module (EAM).
  • To evaluate changes in the number of ASP interventions and antimicrobial utilization.
  • To determine the effect on clinical outcomes following EAM implementation.

Main Methods:

  • Retrospective analysis of data before and after EAM implementation.
  • Monitoring of antimicrobial prescription data and clinical outcomes.
  • Tracking of ASP review and intervention metrics within the EAM.

Main Results:

  • Significant increase in the number of ASP antimicrobial reviews and interventions post-EAM.
  • Sustained impact on reducing overall antimicrobial utilization.
  • No adverse effects on key clinical outcomes observed.

Conclusions:

  • The Epic antimicrobial stewardship module (EAM) is effective in enhancing ASP activities.
  • EAM implementation leads to improved antimicrobial stewardship and utilization.
  • EAM supports sustained antimicrobial reduction without compromising patient care.

Related Concept Videos

Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
1.0K
Antimicrobial Proteins01:23

Antimicrobial Proteins

Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
14.5K
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents01:18

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
471
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy01:16

Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy

Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
1.3K
Nursing Interventions I: Taxonomy of Nursing Interventions01:03

Nursing Interventions I: Taxonomy of Nursing Interventions

Nursing interventions are chosen as part of the planning process to achieve patient outcomes. Once nursing diagnoses are determined, the goals and outcomes are specified, then the nursing interventions are selected and individualized according to the patient's situation.
A nursing intervention is a treatment or action based on scientific concepts and knowledge from the nursing, behavioral, and physical sciences. Identifying and prioritizing nursing interventions based on the desired outcome...
3.9K
Nursing Interventions II: Selecting and Classifying the Nursing Interventions01:29

Nursing Interventions II: Selecting and Classifying the Nursing Interventions

Creating and executing a nursing diagnosis helps nurses plan care and guide patient, family, and community interventions. They are developed based on a patient's physical evaluation and support measuring the outcomes. It is not recommended to select random interventions throughout the planning process. Instead, consider the following six essential factors when choosing interventions:
3.4K