Dystrophic Calcifications in the Breast from Secondary Hyperparathyroidism

Area of Science:

• Nephrology
• Radiology
• Pathology

Background:

• Soft tissue calcification is a known complication of secondary hyperparathyroidism in patients undergoing long-term hemodialysis.
• Breast parenchymal calcifications are uncommon manifestations of this condition.

Purpose of the Study:

• To report a rare case of dystrophic breast calcifications secondary to hyperparathyroidism.
• To emphasize the importance of accurate diagnosis and differentiation from malignancy.

Main Methods:

• A 65-year-old female patient with end-stage renal disease presented with a palpable breast mass.
• Mammography and ultrasound revealed extensive dystrophic calcifications in both breasts.
• Core needle biopsy confirmed dystrophic calcification in the breast stroma.

Main Results:

• Pathological diagnosis confirmed dystrophic calcification secondary to hyperparathyroidism.
• Imaging findings showed extensive calcifications within the breast parenchyma.

Conclusions:

• Dystrophic breast calcifications associated with secondary hyperparathyroidism are rare but important to recognize.
• Accurate diagnosis aids in differentiating these benign lesions from breast malignancies, preventing unnecessary interventions.