Related Experiment Video

Updated: Feb 8, 2026

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy
07:20

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy

Published on: August 9, 2024

2.0K

Prophylactic antibiotics in soft-tissue procedures in children with cerebral palsy

L R Perotti1, O Abousamra1, K J Rogers1

  • 1Department of Orthopedics, Nemours/Alfred I. duPont Hospital for Children, Wilmington, Delaware, USA.

Journal of Children'S Orthopaedics
|June 29, 2018
PubMed

Insights

Prophylactic antibiotics did not significantly alter surgical site infection rates in pediatric cerebral palsy patients undergoing soft-tissue procedures. This finding suggests routine antibiotic use may not be necessary for these specific surgeries.

Area of Science:

  • Pediatric Orthopedic Surgery
  • Infectious Disease Prevention
  • Cerebral Palsy Management

Background:

  • Limited data exists on perioperative prophylactic antibiotic efficacy in pediatric patients.
  • Cerebral palsy (CP) patients may have unique considerations for surgical site infections (SSIs).

Purpose of the Study:

  • To evaluate the infection rate in pediatric CP patients undergoing isolated soft-tissue procedures.
  • To compare outcomes with and without preoperative prophylactic antibiotics.

Main Methods:

  • Retrospective review of pediatric CP patients undergoing limb soft-tissue procedures (2009-2015).
  • Exclusion of patients with groin incisions and those with <30-day follow-up.
  • Comparison of SSI rates between antibiotic and no-antibiotic groups.

Main Results:

  • The antibiotic group (77 children) had 1 SSI out of 343 procedures.
  • The no-antibiotic group (48 children) had 0 SSIs out of 177 procedures.
  • This indicates a low overall SSI rate in both groups.

Conclusions:

  • Preoperative prophylactic antibiotics did not demonstrate a benefit in reducing SSIs for isolated soft-tissue procedures in pediatric CP patients.
  • Findings suggest current antibiotic prophylaxis protocols may warrant re-evaluation for this patient population.
Abstract

Keywords:
antibioticcerebral palsygroin incisionsurgical site infectiontendon lengthening

More Related Videos

Author Spotlight: Exploring the Potential of Massage Therapy in Cerebral Palsy Using Animal Models08:24

Author Spotlight: Exploring the Potential of Massage Therapy in Cerebral Palsy Using Animal Models

Published on: August 11, 2023

2.7K
Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy08:26

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy

Published on: January 11, 2016

12.6K

Related Concept Videos

Antibiotic Selection00:57

Antibiotic Selection

Overview
60.0K
Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
1.5K
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
312
Cerebral Hemispheres01:05

Cerebral Hemispheres

The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
2.5K
Blind Procedures02:07

Blind Procedures

Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
13.6K
Handwashing II: Pre-procedure and Initial Procedure Steps01:19

Handwashing II: Pre-procedure and Initial Procedure Steps

The pre-procedure steps of handwashing include removing jewelry and rolling up sleeves. However, many organizations allow staff to wear wedding rings.
The hand washing procedure itself includes the following steps. First, cover cuts, if any, on hands with a waterproof dressing. Cuts and abrasions can become contaminated with bacteria hindering the ability to clean the area thoroughly. In addition, repeated hand washing can worsen an injury.  The nails must be short and clean, without nail...
1.6K