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Serpentine Supravenous Hyperpigmentation in an HIV Patient Receiving R-CHOP for DLBCL
Guido Lancman1, Amir Steinberg2, Janice Gabrilove2
1Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Abstract:
Serpentine supravenous hyperpigmentation (SSH) is a rare vasculo-cutaneous entity that has been associated with peripheral infusion of chemotherapy agents, in particular 5-FU1-3, but also seen with docetaxel4,5, fotemustine6, and vinorelbine7. It consists of a marked hyperpigmentation along the superficial network of veins proximal to the chemotherapy infusion site and was originally described in a 1976 case report in association with 5-FU1. Here, for the first time, we report SSH in association with R-CHOP chemotherapy.
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