Related Experiment Video
Updated: Feb 8, 2026
08:25
Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
Published on: September 26, 2022
3.5K
Photocontact Dermatitis and Its Clinical Mimics: an Overview for the Allergist
Margaret Snyder1, Jake E Turrentine2, Ponciano D Cruz3,4
1Division of Dermatology, Medical College of Georgia, Augusta University, 1004 Chafee Ave, FH-100, Augusta, GA, 30904, USA. msnyder@augusta.edu.
Clinical Reviews in Allergy & Immunology
|June 29, 2018
Summary
Photo-contact dermatitis (PCD) is a skin reaction to light and chemicals. Identifying and avoiding the trigger is key to managing this condition which can affect quality of life.
Area of Science:
- Dermatology
- Photodermatology
Background:
- Photo-contact dermatitis (PCD) is an adverse skin reaction from simultaneous exposure to a contactant and light.
- It is classified as photo-allergic or photo-irritant, based on the reaction type.
Purpose of the Study:
- To review the clinical presentation, diagnosis, and management of photo-contact dermatitis.
- To differentiate PCD from its clinical mimics.
Main Methods:
- Review of clinical presentation, differential diagnosis, pathogenic mechanisms, diagnostic testing, and therapeutic considerations.
- Discussion of patch and photopatch testing for diagnosis.
Main Results:
- Common causes include plants, psoralens, internal medications (photo-irritant), and sunscreens, topical NSAIDs (photo-allergic).
- Accurate diagnosis involves history, physical exam, and photopatch testing.
- Differential diagnosis includes conditions like polymorphic light eruption and lupus.
Conclusions:
- Effective management of PCD hinges on identifying and avoiding the causative agent.
- An informed approach to diagnosis and management is crucial for improving patient quality of life.
Keywords:
Photo-allergic dermatitisPhoto-contact dermatitisPhoto-irritant dermatitisPhotopatch testingSolar urticariaMore Related Videos
10:27Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
25.0K
06:47Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
Published on: September 27, 2017
10.2K
Related Concept Videos
01:11Clinical Trials: Overview
5.0K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
5.0K
01:27Nursing Clinical Information System
1.3K
Nursing Clinical Information System (NCIS)
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
1.3K
01:16Clinical Trials
10.8K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
10.8K
01:40Overview of Metabolism
38.5K
Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
38.5K
01:19Overview of Functional Groups
16.4K
Functional groups are a group of atoms with characteristic properties, which when linked to the carbon skeleton of a molecule, alter the properties of that molecule. For example, certain functional groups will make a molecule hydrophilic, whereas others will make them hydrophobic. These functional groups are an indispensable part of organic chemistry and important components of biological molecules, such as carbohydrates, proteins, lipids, and nucleic acids. Each functional group is a unique...
16.4K
01:10Pharmacokinetics: Overview
9.7K
Pharmacokinetics is a scientific discipline that focuses on the journey of a drug within the body, encompassing four key stages: absorption, distribution, metabolism, and elimination. The first stage, absorption, involves the drug's transfer into the bloodstream. Several factors dictate the extent and speed of this process. For example, the liver often metabolizes oral drugs before they reach systemic circulation, leading to only partial absorption. In contrast, intravenous (IV)...
9.7K