Normal pancreatic parenchymal thickness by CT in healthy children

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Andrew T Trout1,2,3, Kamal Preet-Singh4, Christopher G Anton5,6

  • 1Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., MLC 5031, Cincinnati, OH, 45229, USA. andrew.trout@cchmc.org.

Pediatric Radiology
|June 29, 2018
PubMed

Insights

This study establishes normal pancreatic thickness ranges in children, crucial for diagnosing pancreatic atrophy. These measurements vary with age and size, aiding in objective pediatric pancreatitis assessment.

Area of Science:

  • Pediatric Radiology
  • Gastroenterology
  • Medical Imaging

Background:

  • Chronic pancreatitis is increasingly diagnosed in children, but assessing atrophy is currently qualitative.
  • Defining normal pancreatic size in children is essential for quantitative atrophy measurement.

Purpose of the Study:

  • To establish normal pancreatic thickness ranges at multiple anatomical locations in healthy children.
  • To provide quantitative data for the objective assessment of pancreatic atrophy in pediatric patients.

Main Methods:

  • Retrospective analysis of computed tomography (CT) scans from 140 healthy children aged 3-16.99 years.
  • Pancreatic thickness measured at head, neck, body, and tail by three reviewers.
  • Statistical analysis included inter-reviewer agreement (ICC) and correlation with age, height, and weight (Spearman's rho).

Main Results:

  • Normal pancreatic thickness ranges were defined: head (1.3-2 cm), neck (0.7-1 cm), body (0.9-1.6 cm), and tail (1-1.6 cm), varying with age.
  • Inter-reviewer agreement was fair to good (ICC: 0.52-0.7).
  • Pancreatic thickness showed weak to moderate correlation with age, height, and weight.

Conclusions:

  • Normal pancreatic thickness ranges in children have been established.
  • These measurements are influenced by patient age and body size.
  • The data can facilitate objective diagnosis of pancreatic atrophy in pediatric patients.
Abstract

Keywords:
ChildrenComputed tomographyPancreasPancreatitis

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