Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Long-patch Base Excision Repair

Long-patch Base Excision Repair

Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:

Convergent Evolution

Convergent Evolution

Evolution shapes the features of organisms over time, ensuring that they are suited for the environments in which they live. Sometimes, selection pressure leads to the rise of similar but unrelated adaptations in organisms with no recent common ancestors, a process known as convergent evolution.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The role, evaluation, and effects of comorbidities in patients with chronic rhinosinusitis.

The journal of allergy and clinical immunology. In practice·2026

Same author

Lost and Found: Is Olfactory Recovery More Promising After COVID-19 Than Other Causes, Even 2 Years Later?

International forum of allergy & rhinology·2026

Same author

Chronic Sinusitis With Orbitonasal Bony Defect.

JAMA otolaryngology-- head & neck surgery·2026

Same author

Uncovering Cystic Fibrosis Carrier: Insights From a Heterozygous CFTR-F508del Rabbit Model.

International forum of allergy & rhinology·2026

Same author

Multi-Layer Endoscopic Repair of Anterior Skull Base Defects.

Otolaryngologic clinics of North America·2026

Same author

Utilizing a publicly accessible automated machine learning platform to enable diagnosis before tumor surgery.

Communications medicine·2025

Same journal

Clinical Efficacy of Tezepelumab in Moderate-to-Severe Uncontrolled Chronic Rhinosinusitis with Nasal Polyps: A Systematic Review of Randomized Controlled Trials.

American journal of rhinology & allergy·2026

Same journal

Cancer Metastasis to the Sinonasal Cavity: Clinical Characteristics and Survival Analysis in 35 Patients.

American journal of rhinology & allergy·2026

Same journal

Implementation and Outcomes of a Structured Epistaxis Protocol in Hereditary Hemorrhagic Telangiectasia: An Observational Cohort Study from a Multidisciplinary Clinic.

American journal of rhinology & allergy·2026

Same journal

Large-Scale Three-Dimensional CT Mapping of the Frontal Sinus Drainage Pathway: Anatomical Relationships and Surgical Validation.

American journal of rhinology & allergy·2026

Same journal

Comparative Restenosis and Revision Rates of Draf IIB Versus Draf III Frontal Sinusotomy in Chronic Rhinosinusitis: A Meta-Analysis Stratified by Endotype.

American journal of rhinology & allergy·2026

Same journal

Adjuvant Radiotherapy Does Not Improve Overall Survival After Negative Margin Resection of Sinonasal Epithelial-Myoepithelial Carcinoma.

American journal of rhinology & allergy·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Feb 8, 2026

Engineered Vascularized Muscle Flap

Engineered Vascularized Muscle Flap

Published on: January 11, 2016

Osteoplastic Flap Without Obliteration: How I Do It.

Catherine G Banks¹, Jaime A P Garcia¹, Jessica Grayson¹

¹1 Department of Otolaryngology, University of Alabama-Birmingham, Birmingham, Alabama.

American Journal of Rhinology & Allergy

|June 29, 2018

Summary

This summary is machine-generated.

This study introduces an osteoplastic flap technique without obliteration, preserving frontal sinus function. This approach offers excellent surgical access for large tumors and reduces long-term complications.

Keywords:

Draf 3 Draf III osteoma osteoplastic flap osteoplastic flap without obliteration outside-in

More Related Videos

An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps

An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps

Published on: December 5, 2025

A Model of Free Tissue Transfer: The Rat Epigastric Free Flap

A Model of Free Tissue Transfer: The Rat Epigastric Free Flap

Published on: January 15, 2017

Related Experiment Videos

Last Updated: Feb 8, 2026

Engineered Vascularized Muscle Flap

Engineered Vascularized Muscle Flap

Published on: January 11, 2016

An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps

An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps

Published on: December 5, 2025

A Model of Free Tissue Transfer: The Rat Epigastric Free Flap

A Model of Free Tissue Transfer: The Rat Epigastric Free Flap

Published on: January 15, 2017

Area of Science:

Neurosurgery
Otolaryngology
Skull Base Surgery

Background:

Osteoplastic flap is a common approach for frontal sinus pathology.
Obliteration, often performed with this flap, can lead to significant long-term complications.

Purpose of the Study:

To describe an alternative osteoplastic flap technique without obliteration.
To evaluate the feasibility and benefits of this non-obliterated approach.

Main Methods:

Descriptive analysis of the non-obliterated osteoplastic flap technique.
Demonstration of a combined approach using Draf III for large frontal sinus osteoma removal.

Main Results:

The osteoplastic flap without obliteration preserves frontal sinus function.
It provides direct access to the frontal sinus.
The combined approach facilitated removal of a large frontal sinus osteoma.

Conclusions:

This technique offers excellent exposure for large tumors not amenable to purely endoscopic procedures.
It allows for improved post-operative surveillance.
Minimizes long-term complications associated with obliterated sinuses.