Related Experiment Video
Updated: Feb 8, 2026

Three-Dimensional Shape Modeling and Analysis of Brain Structures
Published on: November 14, 2019
[Dome-shaped macula: features of differential diagnostics with clinical examples]
M V Melikhova1, M V Gatsu2, E V Boiko2
1Saint Petersburg branch of S. Fyodorov Eye Microsurgery Federal State Institution, 21 Yaroslava Gasheka St., St. Petersburg, Russian Federation, 192283.
Dome-shaped macula (DSM) can be mistaken for choroidal hemangioma (HC). Enhanced depth imaging optical coherence tomography (EDI-OCT) is key for differentiating these conditions, with FA and MRI useful in complex cases.
Area of Science:
- Ophthalmology
- Medical Imaging
Background:
- Dome-shaped macula (DSM) is characterized by posterior pole protrusion due to scleral thickening.
- DSM can present with complications like serous retinal detachment (SRD), mimicking choroidal hemangioma (HC).
- Accurate differentiation is crucial for appropriate patient management.
Purpose of the Study:
- To illustrate differential diagnostic capabilities for DSM versus HC using advanced imaging.
Main Methods:
- Two clinical cases of DSM with HC were examined.
- Diagnostic tools included enhanced depth imaging optical coherence tomography (EDI-OCT), OCT angiography, fluorescent angiography (FA), indocyanine-green angiography (ICG), and MRI.
Main Results:
- EDI-OCT is the primary, highly informative method for differentiating DSM and HC.
- FA and MRI are recommended for challenging differential diagnoses.
- OCT angiography and ICG angiography aid in identifying the cause of SRD in DSM.
Conclusions:
- Low awareness of DSM contributes to diagnostic difficulties.
- Ophthalmoscopy alone is often insufficient for DSM detection.
- Utilizing EDI-OCT, FA, and MRI, with correct interpretation, can prevent diagnostic errors.
Related Concept Videos
Pericarditis II: Clinical Features and Diagnostic Tests
Myocarditis II: Clinical Features and Diagnostic Tests
Mitral Regurgitation II: Clinical Features and Diagnostic Tests
Mitral Stenosis II: Clinical features and Diagnostic Tests
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:

