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The Henderson-Hasselbalch Equation : A Three Dimensional Teaching Model.

Vinay Oommen, Gnanasenthil Ganesh, Kamalakannan Vadivel

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    |June 29, 2018
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    Summary

    Three-dimensional models of the Henderson-Hasselbalch equation enhance understanding of acid-base physiology. These models visualize the complex relationship between PaCO2, bicarbonate, and blood pH beyond traditional 2D plots.

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    Area of Science:

    • Physiology
    • Medical Education

    Background:

    • The Henderson-Hasselbalch equation is fundamental to acid-base physiology.
    • Conventional 2D plots simplify but don't fully represent the equation's 3D nature.
    • Acid-base disorders involve complex interactions of PaCO2, [HCO3—], and blood pH.

    Purpose of the Study:

    • To create and evaluate 3D models of the Henderson-Hasselbalch equation.
    • To improve student comprehension of acid-base balance.
    • To offer supplementary teaching tools beyond 2D nomograms.

    Main Methods:

    • Constructed two distinct 3D models of the Henderson-Hasselbalch surface using accessible materials.
    • Model 1: Discrete points using beads, rods, and plywood.
    • Model 2: Continuous surface using polystyrene and cement.

    Main Results:

    • The 3D models effectively visualized the Henderson-Hasselbalch surface.
    • Both models were presented to medical students alongside traditional 2D methods.
    • Students found the 3D models beneficial for understanding acid-base physiology.

    Conclusions:

    • Three-dimensional models offer a valuable supplement to conventional teaching methods for acid-base physiology.
    • Visualizing the Henderson-Hasselbalch equation in 3D aids in understanding complex physiological relationships.
    • These models can deepen students' grasp of acid-base disorders and their underlying biochemical principles.