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Epilepsy in Asia: Disease burden, management barriers, and challenges
Eugen Trinka1,2, Patrick Kwan3, ByungIn Lee4
1Department of Neurology, Christian Doppler Klinik, University Hospital Paracelsus Medical University, Salzburg, Austria.
Epilepsy affects millions globally, with 80% in low-resource nations. Many in Asia face stigma and inadequate treatment, highlighting the need for improved epilepsy care and research.
Area of Science:
- Neurology
- Public Health
- Global Health
Background:
- Epilepsy is a significant global health issue, impacting up to 70 million individuals worldwide.
- A disproportionate burden, nearly 80%, resides in low- and middle-income countries with limited resources.
- Individuals with epilepsy experience higher rates of physical and psychological comorbidities, including anxiety and depression, impacting quality of life and increasing premature mortality risk.
Purpose of the Study:
- To review the burden of epilepsy in Asia.
- To examine the challenges faced by people with epilepsy in the region.
- To assess the current management and treatment landscape of epilepsy in Asia compared to global standards.
Main Methods:
- A narrative review approach was employed.
- Data were systematically collected using specified search criteria.
- Included articles focused on epilepsy epidemiology, diagnosis, comorbidities, mortality, stigmatization, and treatment.
Main Results:
- Stigmatization is prevalent in Asia, affecting education, employment, and marriage.
- Access to epilepsy treatment is highly variable; up to 90% in resource-limited areas receive inadequate or no conventional antiepileptic therapy.
- While advanced treatments and epilepsy surgery exist in some Asian countries, they are often underutilized and inaccessible, particularly in remote regions.
Conclusions:
- Significant gaps exist in epilepsy management and access to care across Asia, particularly in resource-limited settings.
- Further epidemiologic research is crucial for accurate data collection and targeted interventions.
- Coordinated regional and global efforts are essential to improve epilepsy treatment access and overall care for affected individuals.
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