Rapidly progressing central-type primitive neuroectodermal tumor of the ovary: a case report

Area of Science:

• Neuro-oncology
• Gynecologic oncology
• Pathology

Background:

• Primitive neuroectodermal tumors (PNET) are rare, highly malignant neoplasms of neuroectodermal origin.
• PNETs are classified as either peripheral-type (Ewing family tumors) or central-type.
• While PNETs can occur in gynecologic organs, they are uncommon, and prognosis is typically poor.

Observation:

• This report focuses on a 53-year-old woman presenting with a rapidly progressing ovarian mass.
• Diagnostic evaluation revealed a central-type Primitive neuroectodermal tumor of the ovary.

Findings:

• The case illustrates a rare occurrence of central-type PNET in the ovary.
• The tumor exhibited rapid progression, consistent with the aggressive nature of PNETs.
• The patient's presentation underscores the diagnostic challenges and poor prognosis associated with ovarian PNET.

Implications:

• This case contributes to the limited literature on ovarian PNET, particularly the central-type.
• Highlights the importance of considering rare malignancies in the differential diagnosis of ovarian masses.
• Emphasizes the need for prompt diagnosis and aggressive management strategies for PNET in gynecologic organs.