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Updated: Feb 8, 2026

Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity
Published on: March 16, 2018
[Balloon dilation oft the Eustachian tube in tympanic membrane retraction]
Laura Esther Huhnd1, Stefan P Wirtz2, Thomas Schrom1
1HELIOS Klinikum Bad Saarow Klinik für Hals-, Nasen-, Ohrenheilkunde, Kopf- und Halschirurgie, plastische Operationen.
Objective:
A tube dysfunction is a common medical issue and can promote chronic otitis media. With the implementation of the Balloon dilation a treatment of the chronic tube dysfunction was set. In the present study significance of this method was assessed, especially questioning the success in practical terms of tympanic membrane retraction.
Material And Methods:
In a retrospective study, in a period of assessment from 2011 until 2016, the data of 81 patients, who underwent Balloon dilation of the Eustachian tube due to chronic tube dysfunction with regard to a preoperative presence of tympanic membrane retraction were evaluated. The success of the Balloon dilation was judged due to the capability of a postoperative SVT- Test and the patients' self-assessment. With an average postoperative period of four months, the data of 13 patients were analyzed based on presence of pre- and postoperative tympanic membrane retraction.
Results:
The treatment occurred at all cases without complications. In patients with chronic tube dysfunction the method revealed an improvement of 46 %, while 31 % of the patients with tympanic membrane retraction showed an improvement of the middle ear ventilation. Subjectively perceived 54 % of the patients marked an improvement of their clinical symptoms.
Conclusion:
In spite of a self-assessed improvement in 54 % only 31 % of the patients with chronic membrane retraction showed an objectively measurable success. To evaluate the question if combination with other middle ear surgeries shows better results, further studies, including more patients and data, are required.
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