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Updated: Feb 8, 2026

Microfluidic Dry-spinning and Characterization of Regenerated Silk Fibroin Fibers
Published on: September 4, 2017
High-Throughput Preparation of Silk Fibroin Nanofibers by Modified Bubble-Electrospinning
Yue Fang1, Lan Xu2, Mingdi Wang3
1National Engineering Laboratory for Modern Silk, College of Textile and Engineering, Soochow University, 199 Ren-ai Road, Suzhou 215123, China. yfang5279@stu.suda.edu.cn.
Abstract:
As a kind of natural macromolecular protein molecule extracted from silk, silk fibroin (SF) has been widely used as biological materials in recent years due to its good physical and chemical properties. In this paper, a modified bubble-electrospinning (MBE) using a cone-shaped gas nozzle combined with a copper solution reservoir was applied to obtain high-throughput fabrication of SF nanofibers. In the MBE process, sodium dodecyl benzene sulfonates (SDBS) were used as the surfactant to improve the spinnability of SF solution. The rheological properties and conductivity of the electrospun SF solutions were investigated. And the effects of gas flow volume, SF solution concentration and additive amounts of SDBS on the morphology, property and production of SF nanofibers were studied. The results showed the decrease of gas flow volume could decrease the nanofiber diameter, enhance the diameter distribution, and increase the production of nanofibers. And the maximum yield could reach 3.10 g/h at the SF concentration of 10 wt % and the SDBS concentration of 0.1 wt %.
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