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Updated: Feb 8, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
Published on: August 11, 2008
Second month sputum smear as a predictor of tuberculosis treatment outcomes in Brazil
Maria do Socorro Nantua Evangelista1,2,3, Rosalia Maia4, João Paulo Toledo4
1Brazil, Ministry of Health, National Tuberculosis Program, Federal District, Brasília, Brazil. socorrok@unb.br.
Objective:
The value of sputum smear microscopy (SSM) after 2 months of treatment in the management of pulmonary tuberculosis is controversial. We analysed second month-SSM conversion as a predictor of treatment success in Brazil.
Results:
Overall successful outcome rate was 89.4%. The predictive value of second month-SSM conversion for successful outcomes was 85.2% 72,479/85,118), while the predictive value of non-conversion for unfavourable outcomes was 26.9% (2712/10,071). Unfavourable treatment outcomes were twice more likely among patients who did not convert (adjusted OR = 2.06; 1.97-2.16).
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