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Updated: Feb 8, 2026

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
Published on: December 5, 2015
[Maternal smoking during pregnancy: A risk factor for respiratory disorders in children]
1Département de pharmacologie, CESP-Inserm 1018, hôpital Pitié-Salpêtrière, faculté de médecine,Sorbonne université, 47-83, boulevard de l'Hôpital, 75013 Paris, France.
Abstract:
Maternal smoking during pregnancy (MSDP) is a well-established risk factor for negative pregnancy outcomes, but its negative effects on the health of the child after birth are less well known by both health professionals and the general public. Large cohort studies over the past 10 years have shown that MSDP is an independent risk factor for several childhood health problems such as e.g. obesity and smoking. A large number of recent studies and 3 meta-analyses demonstrate that MSDP is an independent risk factor of wheezing and asthma of the child exposed in utero to maternal smoking. MSDP is associated with epigenetic toxicities the currently most plausible hypothesis to explain the diversity of its postnatal negative effects. The eradication of MSDP could contribute to the reduction of health problems in the next generation, including the incidence of childhood respiratory disorders.
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