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Frequency of Cardiac Rhythm Abnormalities in a Half Million Adults

Shaan Khurshid1, Seung Hoan Choi2, Lu-Chen Weng2

  • 1Division of Cardiology (S.K.).

Circulation. Arrhythmia and Electrophysiology
|June 30, 2018
PubMed

Insights

Cardiac rhythm abnormalities are common in adults, particularly older individuals. Atrial fibrillation and bradyarrhythmias are the most frequent types, with age and hypertension being key risk factors.

Area of Science:

  • Cardiology
  • Epidemiology
  • Public Health

Background:

  • Cardiac rhythm abnormalities are prevalent in community-dwelling adults but not well-characterized.
  • Understanding their frequency and risk factors is crucial for public health initiatives.

Purpose of the Study:

  • To determine the frequency of cardiac rhythm abnormalities in a large, national prospective cohort.
  • To identify risk factors associated with the incidence of these abnormalities.

Main Methods:

  • Utilized data from the UK Biobank, a prospective cohort of over 500,000 adults.
  • Employed multivariable proportional hazards regression to analyze associations between risk factors and incident rhythm abnormalities.

Main Results:

  • 2.35% of adults had a baseline rhythm abnormality, increasing with age.
  • Atrial fibrillation, bradyarrhythmias, and conduction system diseases were the most common abnormalities.
  • Older age, male sex, hypertension, chronic kidney disease, and heart failure were significant risk factors.

Conclusions:

  • Cardiac rhythm abnormalities are substantial in middle-aged to older adults.
  • Atrial fibrillation, bradyarrhythmias, and conduction system diseases represent the majority of these conditions.
Abstract

Keywords:
atrial fibrillationbradycardiaheart failuretachycardia, supraventriculartachycardia, ventricular

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