Related Experiment Video
Updated: Feb 8, 2026

Wheel Running and Environmental Complexity as a Therapeutic Intervention in an Animal Model of FASD
Published on: February 2, 2017
Effects of a 12-week running programme in youth and adults with complex mood disorders
Laura E Keating1, Suzanna Becker1,2, Katie McCabe3,4
1McMaster Integrative Neuroscience and Discovery, McMaster University, Hamilton, Canada.
Objective:
Although numerous studies suggest a salutary effect of exercise on mood, few studies have explored the effect of exercise in patients with complex mental illness. Accordingly, we evaluated the impact of running on stress, anxiety and depression in youth and adults with complex mood disorders including comorbid diagnoses, cognitive and social impairment and high relapse rates.
Methods:
Participants were members of a running group at St Joseph Healthcare Hamilton's Mood Disorders Program, designed for clients with complex mood disorders. On a weekly basis, participants completed Cohen's Perceived Stress Scale, Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) questionnaires, providing an opportunity to evaluate the effect of running in this population.
Results:
Data collected for 46 participants from April 2012 to July 2015 indicated a significant decrease in depression (p<0.0001), anxiety (p<0.0001) and stress (p=0.01) scores. Whereas younger participant age, younger age at onset of illness and higher perceived levels of friendship with other running group members (ps≤0.04) were associated with lower end-of-study depression, anxiety and stress scores, higher attendance was associated with decreasing BDI and BAI (ps≤0.01) scores over time.
Conclusions:
Aerobic exercise in a supportive group setting may improve mood symptoms in youth and adults with complex mood disorders, and perceived social support may be an important factor in programme's success. Further research is required to identify specifically the mechanisms underlying the therapeutic benefits associated with exercise-based therapy programmes.
More Related Videos
10:31A Multi-Modal Approach to Assessing Recovery in Youth Athletes Following Concussion
Published on: September 25, 2014
07:02An Investigation of the Effects of Sports-related Concussion in Youth Using Functional Magnetic Resonance Imaging and the Head Impact Telemetry System
Published on: January 12, 2011
Related Concept Videos
Traits, Mood, and Subjective Wellbeing
Neuroticism and...
Wald-Wolfowitz Runs Test II
For binary data, runs are identified using symbols such as + and −, or equivalently, 1s and 0s. In...
Wald-Wolfowitz Runs Test I
The test works...
Intrinsically Disordered Proteins
Framing Effects
Effects of Temperature on Free Energy