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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
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Heart failure with mid-range ejection fraction and with preserved ejection fraction.

J Petutschnigg1,2, F Edelmann3,4,5

  • 1Medizinische Klinik mit Schwerpunkt Kardiologie, Charité-Universitätsmedizin Berlin (CVK), Berlin, Germany.

Herz
|June 30, 2018
PubMed
Summary
This summary is machine-generated.

Heart failure remains a leading diagnosis in German hospitals. This review clarifies heart failure with mid-range ejection fraction (HFmrEF) and heart failure with preserved ejection fraction (HFpEF) to reduce confusion.

Keywords:
Cardiac failureEtiologyExercise and trainingHeart failure therapyStroke volume

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Area of Science:

  • Cardiology
  • Internal Medicine

Background:

  • Heart failure (ICD I50) is the leading diagnosis for hospitalized patients in Germany.
  • Echocardiography and cardiac biomarkers aid in diagnosing heart failure.
  • The 2016 European Society of Cardiology guidelines introduced heart failure with mid-range ejection fraction (HFmrEF).

Purpose of the Study:

  • To clarify the classification of HFmrEF and HFpEF.
  • To reduce confusion surrounding the new HFmrEF classification.
  • To highlight key findings regarding HFmrEF and HFpEF.

Main Methods:

  • Review of published literature on heart failure classifications.
  • Analysis of diagnostic parameters including echocardiography and biomarkers.
  • Synthesis of current understanding of HFmrEF and HFpEF.

Main Results:

  • HFmrEF and HFpEF together account for half of all heart failure cases.
  • Etiology and treatment strategies differ significantly between HFmrEF and HFpEF.
  • The introduction of HFmrEF has caused confusion within the medical community.

Conclusions:

  • Further elucidation of HFmrEF is necessary.
  • Distinguishing between HFmrEF and HFpEF is crucial for appropriate patient management.
  • This review aims to provide clarity on these heart failure classifications.