Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Polyneuropathy in paraproteinaemia.

C Meier

    Journal of Neurology
    |January 1, 1985
    PubMed
    Summary

    Paraproteinaemias often cause peripheral neuropathies, including polyneuropathy. Immunoelectrophoresis is key for diagnosing unknown neuropathies, revealing diverse subtypes and guiding treatment.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Chemical treatment rescues reduced growth of the autoimmune mutant chs3-2D without compromising its immune responses.

    Plant biology (Stuttgart, Germany)·2026
    Same author

    Bone microstructure and TBS in diabetes: what have we learned? A narrative review.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2025
    Same author

    Minimally invasive lateral plating for diaphyseal fractures with extension into the proximal humerus and its implications for the deltoid muscle and its distal insertion: functional analysis and MR-imaging.

    BMC musculoskeletal disorders·2023
    Same author

    In infertile women with subclinical hypothyroidism, with or without thyroid peroxidase antibodies, serum TSH during pregnancy follows preconception values and thyroid hormones remain stable.

    Human reproduction open·2023
    Same author

    Measurement of polarization observables <math></math>, <math></math>, and <math></math> in <math></math> and <math></math> photoproduction off quasi-free nucleons.

    The European physical journal. A, Hadrons and nuclei·2023
    Same author

    Single <math></math> production off neutrons bound in deuteron with linearly polarized photons.

    The European physical journal. A, Hadrons and nuclei·2021

    Area of Science:

    • Neurology
    • Immunology
    • Oncology

    Background:

    • Paraproteinaemias, including monoclonal gammopathies, are frequently linked to peripheral neuropathies.
    • Conditions like Waldenström's macroglobulinaemia and myeloma can manifest as polyneuropathy.
    • Peripheral neuropathies of unknown origin warrant investigation for underlying paraproteinaemia.

    Purpose of the Study:

    • To survey different types of paraproteinaemia and their associated peripheral neuropathies.
    • To discuss the incidence, pathogenesis, and therapy of peripheral neuropathy in monoclonal gammopathies.
    • To highlight the diagnostic importance of immunoelectrophoresis for unexplained polyneuropathies.

    Main Methods:

    • Review of existing literature on paraproteinaemias and peripheral neuropathies.
    • Clinical, electrophysiological, and pathological characterization of neuropathy subtypes.
    • Discussion of diagnostic approaches, including immunoelectrophoresis.

    Main Results:

    • Peripheral neuropathies associated with paraproteinaemia are heterogeneous.
    • Distinct subgroups exist, such as demyelinating neuropathy with IgM paraproteinaemia.
    • Immunoelectrophoresis is a crucial diagnostic tool for identifying these conditions.

    Conclusions:

    • Paraproteinaemia is a significant cause of peripheral neuropathy.
    • Understanding the heterogeneity of these neuropathies is vital for accurate diagnosis and management.
    • Further research into pathogenesis and therapy is warranted.

    Related Experiment Videos