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Updated: Feb 8, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
Published on: March 9, 2018
A Fungal Protease Model to Interrogate Allergic Lung Immunity
J Morgan Knight1, Evan Li1, Hui-Ying Tung2
1Departments of Medicine, Baylor College of Medicine, Houston, TX, USA.
Abstract:
Allergic airway diseases (asthma and chronic rhinosinusitis) are among the most common of all human diseases in heavily industrialized societies. Animal models of asthma have provided remarkable insight into allergic disease pathogenesis and will continue to drive the discovery of new therapeutic insights. We provide in this chapter a detailed protocol for inducing allergic immunity in the lungs of mice using a purified fungal protease and include related protocols for assessing immune endpoints.
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