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Updated: Feb 8, 2026

High Frequency Ultrasound for the Analysis of Fetal and Placental Development In Vivo

High Frequency Ultrasound for the Analysis of Fetal and Placental Development In Vivo

Published on: November 8, 2018

Placental Development and Nutritional Environment.

Kosuke Taniguchi¹, Tomoko Kawai², Kenichiro Hata²

¹Department of Maternal-Fetal Biology, National Research Institute for Child Health and Development, Tokyo, Japan. hata-k@ncchd.go.jp.

Advances in Experimental Medicine and Biology

|June 30, 2018

Summary

Maternal nutrition significantly impacts placental development and epigenetics, influencing fetal and offspring health. Understanding these nutrition-placenta interactions is crucial for developmental biology and evolutionary insights.

Keywords:

DNA methylation Epigenome Genomic imprinting Placenta Retrotransposons

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Area of Science:

Evolutionary biology
Developmental biology
Epigenetics

Background:

The placenta, a recent mammalian evolutionary development, shows diverse morphology despite conserved core functions.
Environmental factors, including nutrition, critically influence placental development and function.
Placental alterations can affect fetal development and long-term offspring health.

Purpose of the Study:

To review current knowledge on placental development, epigenetics, and nutrition.
To highlight the impact of maternal nutrition on the placenta, fetus, and offspring.

Main Methods:

Literature review of studies on placental development, epigenetics, and nutrition.
Synthesis of findings across species, model organisms, and human studies.

Main Results:

Nutrition significantly affects placental formation and function.
Placental changes due to nutrition have downstream effects on fetal and offspring development.
The placenta and epigenome are intricately linked, modulated by nutritional status.

Conclusions:

Maternal nutrition is a key environmental factor influencing placental biology.
Understanding nutrition-placenta-epigenome interactions is vital for fetal and offspring well-being.
Further research is needed to fully elucidate these complex relationships.