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Updated: Feb 8, 2026

A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines
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Published on: March 4, 2017

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Challenges and Opportunities from Basic Cancer Biology for Nanomedicine for Targeted Drug Delivery

Xiaodong Xie1, Yingying Zhang1, Fengqiao Li1

  • 1Cancer Metastasis Alert and Prevention Center, and Pharmaceutical Photocatalysis of State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry; Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, Fuzhou University, Fuzhou, Fujian 350116, China.

Current Cancer Drug Targets
|June 30, 2018
PubMed
Abstract

Insights

Nanotechnology offers promising solutions for cancer treatment by addressing complex hallmarks like metastasis and drug resistance. This review explores nanomaterial interactions to develop targeted nanomedicine for improved cancer therapy.

Area of Science:

  • Oncology
  • Materials Science
  • Nanotechnology

Background:

  • Cancer therapy faces challenges due to complex tumorigenesis and metastasis mechanisms.
  • Current cancer treatments have limitations, driving the need for innovative approaches.
  • Nanotechnology presents significant potential for enhancing cancer treatment strategies.

Purpose of the Study:

  • To review recent advances in understanding cancer hallmarks.
  • To explore the interaction mechanisms between nanomaterials and cancer cells.
  • To identify opportunities for developing mechanism-based nanomedicine for cancer treatment.

Main Methods:

  • Literature review and data collection from relevant articles.
  • Comprehensive analysis of existing research on cancer hallmarks and nanomedicine.

Main Results:

  • Discussed key cancer characteristics: angiogenesis, abnormal vasculature, proliferation, multidrug resistance, metastasis, metabolism, and immune evasion.
  • Highlighted opportunities and challenges for nanomedicine targeting specific cancer cells.
  • Detailed the progress in applying nanotechnology for cancer treatment.

Conclusions:

  • The review provides valuable references for developing effective nanomedicine.
  • Further research into nanomedicine is crucial for advancing cancer treatment.
  • Nanotechnology holds promise for overcoming current therapeutic limitations in oncology.
Keywords:
Nanotechnologycancer characteristicscancer therapynanomedicinetumor angiogenesis.

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