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Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
Published on: February 16, 2024
An overview of anal intraepithelial neoplasia
Corina L Buzard1, Denise Rizzolo
1Corina L. Buzard is chief compliance and quality officer at Carolina Family Health Centers, Inc., in Wilson, N.C. Denise Rizzolo is an associate professor in the School of Nursing at Kean University in Union, N.J., and an assistant clinical professor in the Pace Completion Program in the Department of Physician Assistant Studies in New York City. The authors have disclosed no potential conflicts of interest, financial or otherwise.
Abstract:
Anal intraepithelial neoplasia (AIN) and anal squamous cell carcinoma (ASCC) are on the rise in the United States, especially among men who have sex with men, HIV-positive or other immunocompromised patients, and women with a history of cervical, vaginal, or vulvar cancer. Strong evidence supports the human papillomavirus as the causative factor in anal dysplasia; reducing the risk of HPV infection can reduce rates of ASCC. High-risk patients should be screened for AIN, but no universal screening guidelines exist, and more studies are needed to develop a national protocol for screening and management of patients with AIN.
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