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Published on: September 19, 2019
For T Cells, the Child Is Father of the Man
Kristin A Hogquist1, Sara E Hamilton1
1Department of Laboratory Medicine & Pathology, Center for Immunology, University of Minnesota, Minneapolis, MN, USA.
Abstract:
When T cells respond to infectious agents, they differentiate into effector and memory cells. In this issue of Cell, Smith et al. use a genetic "time-stamping" method to show that the developmental time the T cell arises-near birth or as an adult-dictates what type of T effector or memory cell results.
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