Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Born-Haber Cycle

The Born-Haber Cycle

What are Viruses?

What are Viruses?

Econometric Views (EViews)

Econometric Views (EViews)

Econometric Views, often stylized as EViews, is a package that merges statistical analysis with econometric studies. It is designed to provide tools for time series analysis, forecasting, and econometric model simulation. The software originated from MicroTSP software and has evolved significantly since its inception in 1981. The history of EViews is marked by a continuous effort to enhance its computational speed and user interface. It was initially developed for large computing systems but...

Cranial Bones: Lateral View

Cranial Bones: Lateral View

The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...

Viral Structure

Viral Structure

Viruses are extraordinarily diverse in shape and size, but they all have several structural features in common. All viruses have a core that contains a DNA- or RNA-based genome. The core is surrounded by a protective coat of proteins called the capsid. The capsid is composed of subunits called capsomeres. The capsid and genome-containing core are together known as the nucleocapsid.

Revisionist Views of Adolescent and Adult Cognition

Revisionist Views of Adolescent and Adult Cognition

A revisionist approach to Jean Piaget's theory of cognitive development has brought new insights that challenge and reinterpret his established ideas. Piaget proposed that the formal operational stage, emerging in adolescence, represents the culmination of cognitive maturity. During this stage, individuals are said to develop abstract thinking, engage in systematic problem-solving, and show a form of egocentrism, believing others are as preoccupied with their behavior as they are...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Structures of asymmetric particles of tick-borne encephalitis virus provide insight into flavivirus assembly and maturation.

Science advances·2026

Same author

Structure determination and dual targeting of a plant TACO1 identifies its ancient role as an organelle translation regulator.

bioRxiv : the preprint server for biology·2026

Same author

Influence of the pre-membrane and envelope proteins on structure, pathogenicity, and tropism of tick-borne encephalitis virus.

Journal of virology·2025

Same author

The structure of immature tick-borne encephalitis virus supports the collapse model of flavivirus maturation.

Science advances·2024

Same author

VitroJet: new features and case studies.

Acta crystallographica. Section D, Structural biology·2024

Same author

Community recommendations on cryoEM data archiving and validation.

IUCrJ·2024

Same journal

Correction: Bulatov et al. Camelpox Virus in Western Kazakhstan: Assessment of the Role of Local Fauna as Reservoirs of Infection. <i>Viruses</i> 2024, <i>16</i>, 1626.

Viruses·2026

Same journal

Correction: Franco et al. Whole Blood Volume-Based Absolute Quantification of HTLV-1 Proviral Load: A Comparative Method Evaluation Study. <i>Viruses</i> 2026, <i>18</i>, 580.

Viruses·2026

Same journal

Correction: Medkour et al. Adenovirus Infections in African Humans and Wild Non-Human Primates: Great Diversity and Cross-Species Transmission. <i>Viruses</i> 2020, <i>12</i>, 657.

Viruses·2026

Same journal

Burden of Malaria and Dengue Across Global, Asian, and Chinese Populations Based on GBD 2021 Data: A Quantitative Assessment of Importation Risks to China.

Viruses·2026

Same journal

First Report of <i>Orthonairovirus songlingense</i> in <i>Haemaphysalis concinna</i> Ticks from Russia.

Viruses·2026

Same journal

Epidemiological and Virological Characteristics of H9N2 Avian Influenza Virus in Jiangsu Province, China, 2024.

Viruses·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Feb 8, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

Tick-Borne Encephalitis Virus: A Structural View.

Lauri I A Pulkkinen^1,2, Sarah J Butcher^3,4, Maria Anastasina^5,6

¹HiLIFE-Institute of Biotechnology, University of Helsinki, 00790 Helsinki, Finland. lauri.ia.pulkkinen@helsinki.fi.

|July 1, 2018

Summary

This summary is machine-generated.

Tick-borne encephalitis virus (TBEV) poses a growing health threat. This review highlights current structural knowledge gaps, crucial for developing new TBEV antivirals and diagnostics.

Keywords:

E protein M protein TBEV envelope protein flavivirus structure maturation nucleocapsid prM tick-borne encephalitis virus virus assembly

More Related Videos

Saliva, Salivary Gland, and Hemolymph Collection from Ixodes scapularis Ticks

Saliva, Salivary Gland, and Hemolymph Collection from Ixodes scapularis Ticks

Published on: February 21, 2012

Isolation of microRNAs from Tick Ex Vivo Salivary Gland Cultures and Extracellular Vesicles

Isolation of microRNAs from Tick Ex Vivo Salivary Gland Cultures and Extracellular Vesicles

Published on: April 6, 2022

Related Experiment Videos

Last Updated: Feb 8, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

Saliva, Salivary Gland, and Hemolymph Collection from Ixodes scapularis Ticks

Saliva, Salivary Gland, and Hemolymph Collection from Ixodes scapularis Ticks

Published on: February 21, 2012

Isolation of microRNAs from Tick Ex Vivo Salivary Gland Cultures and Extracellular Vesicles

Isolation of microRNAs from Tick Ex Vivo Salivary Gland Cultures and Extracellular Vesicles

Published on: April 6, 2022

Area of Science:

Virology
Structural Biology
Medical Entomology

Background:

Tick-borne encephalitis virus (TBEV) causes severe neurological disease with rising incidence.
Understanding TBEV structure is crucial but lags behind other flaviviruses.
Knowledge gaps exist in receptor binding, replication, assembly, and tick-host interactions.

Purpose of the Study:

To summarize current structural knowledge of TBEV.
To identify critical gaps in understanding TBEV biology.
To propose future research directions for TBEV structural-functional relationships.

Main Methods:

Review of existing literature on TBEV structure.
Analysis of recent high-resolution structural data of the TBEV virion.
Identification of research areas requiring further investigation.

Main Results:

Recent high-resolution structure of the TBEV virion has advanced understanding.
Significant gaps remain in understanding TBEV's interaction with host receptors.
Limited research exists on TBEV's interaction with its tick vectors.

Conclusions:

Elucidating TBEV structural-functional relationships is essential for therapeutic and diagnostic advancements.
Further research is needed on TBEV-host interactions, particularly with tick vectors.
Addressing knowledge gaps will facilitate the development of effective TBEV antivirals.