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Related Experiment Video

Updated: Feb 8, 2026

Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation
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Infrared Light Structured Sensor Three-dimensional Approach to Estimate Kidney Volume: A Validation Study.

Juan Garisto1, Riccardo Bertolo1, Julien Dagenais1

  • 1Cleveland Clinic, Glickman Urological & Kidney Institute, Cleveland, OH.

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Summary

A new structured-light infrared laser sensor accurately estimates total renal parenchyma volume. This reliable method offers high precision for assessing kidney volume in research and clinical settings.

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Area of Science:

  • Nephrology
  • Medical Imaging
  • Biomedical Engineering

Background:

  • Accurate measurement of total renal parenchyma volume is crucial for diagnosing and managing kidney diseases.
  • Traditional methods for volume estimation can be invasive or lack precision.
  • Novel, non-invasive techniques are needed to improve renal volume assessment.

Purpose of the Study:

  • To validate a novel structured-light infrared laser sensor for the three-dimensional estimation of total renal parenchyma volume.
  • To assess the accuracy and reliability of this new sensor technology in comparison to established methods.

Main Methods:

  • Three experiments were conducted using 20 freshly excised porcine kidneys.
  • Experiment A: Compared sensor-based volume to water displacement method.
  • Experiments B & C: Assessed sensor accuracy after partial kidney excision and repair (renorrhaphy).
  • Statistical analysis included Bland-Altman method for bias and limits of agreement, and intraclass correlation coefficient (ICC) for reliability.

Main Results:

  • Experiment A showed a sensor bias of -1.95mL (LOA: -19.5 to 15.59mL).
  • Experiments B and C demonstrated reduced bias (-0.5mL and -0.89mL respectively) with improved R² values.
  • The intraclass correlation coefficient (ICC) was exceptionally high at 0.9998, indicating excellent reliability.

Conclusions:

  • The structured-light infrared laser sensor provides a reliable and accurate method for assessing total renal volume.
  • This technology holds promise for improving the non-invasive evaluation of renal parenchyma volume.