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Updated: Feb 8, 2026

Simple Bulk Readout of Digital Nucleic Acid Quantification Assays
Published on: September 24, 2015
Readout models for BaFBr0.85I0.15:Eu image plates
1Laboratory for Laser Energetics, University of Rochester, Rochester, New York 14623-1299, USA.
Repeated scanning of photostimulated luminescence image plates enhances dynamic range. New models estimate readout fading by linking activated center depth to signal, improving hard x-ray diagnostics.
Area of Science:
- Medical Physics
- Radiation Detection
- Materials Science
Background:
- Photostimulated luminescence (PSL) imaging plates offer a wide dynamic range for radiation detection.
- Accurate signal quantification is crucial for advanced applications like hard x-ray diagnostics.
- Readout fading in PSL plates can affect signal accuracy over time.
Purpose of the Study:
- To develop and validate models for estimating readout fading in photostimulated luminescence image plates.
- To enhance the dynamic range of PSL imaging through repeated scanning techniques.
- To improve the accuracy of hard x-ray energy spectra measurements using PSL diagnostics.
Main Methods:
- Developed two semi-empirical models to describe readout fading in PSL image plates.
- Estimated model parameters using image plate scan series from BAS-MS plates.
- Utilized the Typhoon FLA 7000 scanner for data acquisition.
- Applied the models to experimental data from hard x-ray diagnostics with double exponential spectra.
Main Results:
- Demonstrated that repeated scanning of PSL image plates significantly extends the extractable dynamic range.
- The introduced models successfully relate the depth distribution of activated PSL centers to the recorded signal, accounting for readout fading.
- Model parameter estimation provided reliable response estimates for the hard x-ray diagnostic system.
Conclusions:
- The linearity of the photostimulated luminescence process supports repeated scanning for extended dynamic range.
- The developed semi-empirical models offer a viable method for correcting readout fading in PSL image plates.
- These advancements enhance the utility of PSL imaging for precise hard x-ray diagnostics.
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