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Author Spotlight: Evaluating Traditional Chinese Therapy for Ankylosing Spondylitis in Mice
Published on: October 27, 2023
Associations Between Cardiorespiratory Fitness and Arterial Stiffness in Ankylosing Spondylitis: A Cross-sectional
Inger Jorid Berg1,2, Anne Grete Semb3,4, Silje H Sveaas3,4
1From the Department of Rheumatology, and the Preventive Cardio-Rheuma Clinic, Diakonhjemmet Hospital, Oslo, Norway; the Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands. ingerjoridberg@gmail.com.
Objective:
To assess associations between cardiorespiratory fitness (CRF), measured as peak oxygen uptake (VO2peak), and cardiovascular disease (CVD) risk, measured by arterial stiffness, in patients with ankylosing spondylitis (AS).
Methods:
VO2peak was assessed by a maximal walking test on a treadmill. Arterial stiffness was measured noninvasively (Sphygmocor apparatus). Cross-sectional associations between VO2peak and arterial stiffness were analyzed using backward multivariable linear regression.
Results:
Among 118 participating patients, there were significant inverse associations between VO2peak and arterial stiffness, independent of traditional CVD risk factors and measures of disease activity.
Conclusion:
Reduced CRF may be related to increased risk of CVD in AS.
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