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Hyperplastic sensory corpuscles in nevus sebaceus of labia minora pudendi. A case report
Jorge Feito1,2, Carmen Cebrián-Muiños3, Elena Julia Alonso-Morrondo1
1Servicio de Anatomía Patológica, Complejo Hospitalario de Salamanca, Salamanca, Spain.
Abstract:
A vulvar case of nevus sebaceus is presented. During the routine histopatological examination, attention was drawn by several corpuscular structures. Immunohistochemistry demonstrated that they were sensory corpuscles, identified respectively as Meissner-like and glomerular corpuscles. Nevertheless, compared with typical Meissner corpuscles from digital glabrous skin, Meissner-like corpuscles identified here were bigger, the axon showed an irregular course, and the lamellar cells were smaller. Regarding the glomerular corpuscles they were bigger but with a normal arrangement of the corpuscular constituents. These findings suggest that these cutaneous sensory corpuscles are part of the nevus sebaceus hamartoma.
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