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Updated: Feb 8, 2026

Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue
Published on: July 28, 2023
A retrospective analysis of surgical resection of large ear keloids
Anqi Lyu1, Erwei Xu1, Qiying Wang1
1The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Objective:
To investigate surgical methods for the removal of larger ear keloids.
Methods:
Two different surgical techniques were used: Method A, tumour excision followed by in situ scar flap repair; and Method B, wedge resection of an auricular lesion followed by primary closure or local flap repair. After the treatment, patients received postoperative, local radiotherapy. Follow-up was for 1-3 years (median 28.9 months).
Results:
Twenty patients with 35 large ear keloids were reviewed. In Method A, six ears were cured, three ears improved, five ears relapsed after 1 year and one ear recurred within 1 year. In Method B, 17 ears were cured, two ears improved and one ear recurred within 1 year.
Conclusion:
Keloid scars can be effectively treated with a combination of radiotherapy and surgical excision.
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