Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ecological Niches02:02

Ecological Niches

26.7K
All organisms have a position within an ecosystem. The complete set of living and nonliving factors—including food resources, climate, and terrain—that define the position of a given organism are collectively referred to as the organism’s ecological niche.
26.7K
Stem Cell Niche01:26

Stem Cell Niche

6.4K
The stem cell niche is the dynamic microenvironment where stem cells reside. Inside these niches, the cells may remain undifferentiated, undergo high self-renewal, or become lineage-specific progenitors. Stem cells coexist with other niche cells, such as stromal cells. They also interact closely with the ECM. Cell-cell and cell-matrix communication occur via adhesion molecules or soluble factors that signal the stem cells and determine their fate. Stromal cells also provide survival signals to...
6.4K
Multipotency and Niche of Bulge Stem Cell01:06

Multipotency and Niche of Bulge Stem Cell

4.2K
A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
4.2K
Induced-fit Model01:13

Induced-fit Model

89.4K
Most chemical reactions in cells require enzymes—biological catalysts that speed up the reaction without being consumed or permanently changed. They reduce the activation energy needed to convert the reactants into products. Enzymes are proteins, that usually work by binding to a substrate—a reactant molecule that they act upon.
Enzymes exhibit substrate specificity, meaning that they can only bind to certain substrates. This is mainly determined by the shape and chemical...
89.4K
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

28.1K
Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
28.1K
Induced Electric Dipoles01:28

Induced Electric Dipoles

4.8K
A permanent electric dipole orients itself along an external electric field. This rotation can be quantified by defining the potential energy because the external torque does work in rotating it. Then, the potential energy is minimum at the parallel configuration and maximum at the antiparallel configuration. While the former is a stable equilibrium, the latter is an unstable equilibrium.
Since the absolute value of potential energy holds no physical meaning, its zero value can be chosen as per...
4.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

IMPACT-Introduction of Mycotic Prophylaxis At Cystectomy Trial: perioperative mycotic prophylaxis with fluconazole to reduce postoperative complications following cystectomy-study protocol for a national multi-center, double-blinded, placebo-controlled, randomized clinical trial.

Trials·2026
Same author

Are preoperative psychological factors associated with chronic postoperative pain after total knee arthroplasty: a systematic review.

EFORT open reviews·2026
Same authorSame journal

Urinary Secretory-IgA and IgG Responses and Inflammatory Markers in Patients With Pseudomonas aeruginosa Urinary Tract Infections.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica·2026
Same author

Association between spasticity of the hip and development of hip displacement in children: a cohort study of 786 hips.

Acta orthopaedica·2026
Same author

Change in bone mineral density after cemented and uncemented knee arthroplasty with an asymmetrical tibial component: secondary analysis of a randomized study using dual-energy X-ray absorptiometry.

Acta orthopaedica·2026
Same author

Hyperbaric Oxygen Treatment as a Novel Add-on in Selected Patients with Infective Endocarditis - A Safety and Feasibility Trial.

Infection and drug resistance·2026

Related Experiment Video

Updated: Feb 8, 2026

Application of Flow Vermimetry for Quantification and Analysis of the Caenorhabditis elegans Gut Microbiome
08:38

Application of Flow Vermimetry for Quantification and Analysis of the Caenorhabditis elegans Gut Microbiome

Published on: March 31, 2023

1.2K

Implants induce a new niche for microbiomes.

Tim H Jakobsen1, Steffen R Eickhardt1, Alexandra G Gheorghe2

  • 1Costerton Biofilm Center, Department of Immunology & Microbiology, University of Copenhagen, Copenhagen, Denmark.

APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica
|July 3, 2018
PubMed
Summary
This summary is machine-generated.

Microbial colonization is common on clinically uninfected medical implants, with both bacteria and fungi frequently detected. This suggests implants alter the human microbiome by creating new niches for microbes.

Keywords:
Implantsforeign bodiesmicrobesmicrobiomenon-pathogenic colonization

More Related Videos

Experimental Model of Ligature-Induced Peri-Implantitis in Mice
05:37

Experimental Model of Ligature-Induced Peri-Implantitis in Mice

Published on: May 17, 2024

3.3K
Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
10:42

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Published on: December 31, 2017

17.9K

Related Experiment Videos

Last Updated: Feb 8, 2026

Application of Flow Vermimetry for Quantification and Analysis of the Caenorhabditis elegans Gut Microbiome
08:38

Application of Flow Vermimetry for Quantification and Analysis of the Caenorhabditis elegans Gut Microbiome

Published on: March 31, 2023

1.2K
Experimental Model of Ligature-Induced Peri-Implantitis in Mice
05:37

Experimental Model of Ligature-Induced Peri-Implantitis in Mice

Published on: May 17, 2024

3.3K
Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
10:42

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Published on: December 31, 2017

17.9K

Area of Science:

  • Microbiology
  • Biomedical Engineering
  • Medical Science

Background:

  • Understanding microbial colonization on medical implants is crucial for preventing infections.
  • Knowledge gaps exist regarding the prevalence of microorganisms on clinically uninfected implants.

Purpose of the Study:

  • To detect and identify bacteria and fungi on implants from patients without signs of infection.
  • To investigate microbial colonization in various patient groups with implants.

Main Methods:

  • Microbiological detection methods were used to analyze 106 clinically uninfected implants and 39 negative controls.
  • Samples were collected from five hospitals in Denmark across four patient groups.

Main Results:

  • 66% of implants showed bacterial colonization, and 40% showed fungal colonization.
  • Prevalent microbes were not typical causes of implant infections.
  • Significant microbial colonization was observed compared to negative controls (p < 0.0001).

Conclusions:

  • Medical implants serve as distinct niches for microbial colonization.
  • The presence of implants can alter the human microbiome.
  • Further research is needed to understand the clinical implications of this colonization.