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Assessment of Coronary Microcirculation During Cardiac Catheterization

Sasko Kedev1, Ivan Vasilev1

  • 1University Clinic of Cardiology, "University Ss Cyril and Methodius" Skopje, Macedonia.

Current Pharmaceutical Design
|July 3, 2018
PubMed

Insights

Functional tests like Fractional Flow Reserve (FFR) and instantaneous wave free ratio (iFR) help identify coronary artery issues. Simpler methods like iFR may improve patient care in cardiac interventions.

Area of Science:

  • Cardiovascular medicine
  • Interventional cardiology

Background:

  • Functional tests complement coronary angiography in diagnosing myocardial blood flow impairment.
  • Fractional Flow Reserve (FFR) is recommended for identifying ischemia-related coronary lesions when other evidence is lacking.

Purpose of the Study:

  • To introduce and evaluate the instantaneous wave free ratio (iFR) as a simpler alternative to FFR.
  • To explore the potential of iFR in enhancing value-based care for coronary interventions.

Main Methods:

  • Comparison of iFR with FFR in functional assessments within the catheterization laboratory.
  • Evaluation of iFR's requirement for vasodilator administration.

Main Results:

  • iFR offers a simpler approach compared to FFR.
  • iFR does not require the administration of vasodilators, unlike FFR.

Conclusions:

  • The instantaneous wave free ratio (iFR) is a promising, user-friendly alternative to FFR.
  • Simpler techniques like iFR have the potential to advance value-based care in coronary interventions.

Keywords:
Cardiac catheterizationCoronary microcirculationFractional Flow Reserve (FFR)Instantaneous wave free ratio (iFR)computer tomography CT- derived fractional flow reserve FFRCTcoronary angiography.

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