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Comparison between Three-Dimensional Navigator-Gated Whole-Heart MRI and Two-Dimensional Cine MRI in Quantifying

Hyun Woo Goo1

  • 1Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea.

Korean Journal of Radiology
|July 3, 2018
PubMed

Insights

Three-dimensional (3D) whole-heart MRI offers improved timing accuracy over two-dimensional (2D) cine MRI for ventricular volume quantification. However, 3D whole-heart MRI may underestimate right ventricular stroke volumes due to early end-diastole phase timing.

Area of Science:

  • Cardiovascular Imaging
  • Medical Physics

Background:

  • Accurate quantification of ventricular volumes is crucial for assessing cardiac function, particularly in congenital heart disease.
  • Conventional two-dimensional (2D) cine magnetic resonance imaging (MRI) is widely used but may have limitations in temporal accuracy and volume measurement.
  • Three-dimensional (3D) whole-heart MRI offers potential advantages in capturing cardiac anatomy and function.

Purpose of the Study:

  • To compare the accuracy of ventricular volume quantification between 3D whole-heart MRI and 2D cine MRI.
  • To evaluate the temporal accuracy of cardiac trigger delays in both imaging modalities.
  • To assess the agreement between calculated stroke volumes and direct arterial flow measurements.

Main Methods:

  • 110 patients with congenital heart disease underwent navigator-gated 3D whole-heart MRI and 2D short-axis cine MRI.
  • Ventricular volumes were measured using 3D segmentation and 2D contouring methods.
  • Cardiac trigger delays were compared, and stroke volumes were validated against phase contrast MRI of great arteries.

Main Results:

  • 3D whole-heart MRI demonstrated significantly shorter end-systole and end-diastole trigger delays compared to 2D cine MRI for both ventricles (p < 0.001).
  • 2D cine MRI significantly overestimated left ventricular stroke volumes (8.7 ± 8.9 mL, p < 0.001).
  • 3D whole-heart MRI significantly underestimated right ventricular stroke volumes (-22.7 ± 22.9 mL, p < 0.001).

Conclusions:

  • While 3D whole-heart MRI offers improved temporal resolution, it may lead to underestimation of right ventricular stroke volumes.
  • Early timing of the end-diastole phase in 3D whole-heart MRI can impact the accuracy of right ventricular volume assessment.
  • Further optimization of 3D whole-heart MRI acquisition and analysis is needed for precise ventricular volume quantification.
Abstract

Keywords:
CMRCardiac MRCardiac volumetric quantificationCongenital heart diseaseSimplified contouringThreshold-based segmentation

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