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Updated: Feb 8, 2026

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
Published on: May 19, 2020
Aortic and mitral valve repair for anterior mitral leaflet perforation caused by severe aortic regurgitation
Kristof De Brabandere1, Jens-Uwe Voigt2, Stephen Rex3
1Department of Cardiac Surgery, UZ Leuven, Leuven, Belgium.
Abstract:
A 23-year-old man presented with acute onset of dyspnea on exert. Preoperative echocardiography showed a severe regurgitation of the bicuspid aortic valve (due to prolapse of the fused cusp) creating a jet directed through the defect in the anterior leaflet of the mitral valve. Both valves were repaired. Endocarditis was excluded with cultures and polymerase chain reaction (PCR). Postoperative course was uneventful.
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